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KMID : 0361720070180020168
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Korean Journal of perinatology
2007 Volume.18 No. 2 p.168 ~ p.172
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A Case of Preeclampsia Complicating a Pregnancy with Malignant Neurofibromatosis
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Jeong Eun-Young
Lee Kwon-Hae
Kim Jeong-Sig
Nam Kye-Hyun
Kim Tae-Hee
Lee Hae-Hyeog
Lee Jung-Jae
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Abstract
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Neurofibromatosis type 1 (NF-1) is one of the most common genetic disorders, occurring once in every 4000 births. The prevalence of neurofibromatosis associated with pregnancy was one in 5000~18500 deliveries. Higher rates of maternal and neonatal complications have been reported in NF-1 patients including as hypertension, intrauterine growth restriction (IUGR), preterm labor, stillbirth and cesarean section rates. Thus, pregnant patients with NF-1 are required close antenatal observation at high risk tertiary centers in order to detect complication early. We report a case of malignant neurofibromatosis associated with pregnancy with a review of literature.
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KEYWORD
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Pregnancy, Neurofibromatosis, Preeclampsia, Intrauterine growth retardation
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